BPC-157 & TB-500 — Research Peptide Blend
BPC-157 (Pentadecapeptide BPC-157) 10mg and TB-500 10mg (synthetic thymosin beta-4 analog)
are laboratory peptides explored separately in preclinical models for roles in tissue protection and repair.
Together, they are often studied as a complementary blend: BPC-157 for endothelial/angiogenic and
matrix-oriented signaling; TB-500 for cytoskeletal dynamics, cell migration, and wound remodeling.
What They Are
- BPC-157: 15-amino-acid pentadecapeptide studied for effects on endothelial integrity,
angiogenic signaling, nitric-oxide–linked pathways, and collagen matrix organization. - TB-500: 43-amino-acid analog of thymosin ?4, examined for actin binding/sequestration,
cell motility, microtubule/cytoskeleton remodeling, and re-epithelialization in injury models.
Proposed Mechanisms (Preclinical)
BPC-157
- Endothelial protection & pro-angiogenic signaling (NO-linked pathways; early-growth-response factors).
- Matrix/collagen support and fibroblast migration in tendon/ligament models.
- Inflammation modulation and potential neuroprotective signaling (model-dependent).
TB-500
- Actin-binding motif
LKKTETQassociated with cytoskeletal reorganization and cell motility. - Wound-healing biology: re-epithelialization, angiogenesis, granulation-tissue quality (model-dependent).
- Inflammation-pathway modulation (e.g., miR-146a/IRAK1/TRAF6 axis, exploratory).
Selected Research Highlights
- Skin/Wound Models: TB-500 (T?4) associated with faster re-epithelialization and contraction vs. controls in animal studies; small clinical datasets in chronic wounds have explored dose-response over multi-week protocols.
- Tendon/Ligament: TB-family peptides reported more organized collagen and improved mechanical properties post-injury; BPC-157 associated with fibroblast migration and collagen deposition in tendon explants.
- Muscle: BPC-157 explored in steroid-injury muscle models for functional restoration; TB-family peptides investigated for cytoskeletal remodeling and angiogenesis in cardiac ischemia models.
- Angiogenesis & Matrix: Both peptides studied for capillary density/neo-vessel formation and ECM organization under injury stressors.
Chemical Information
- BPC-157 — Formula: C62H98N16O22 · MW: 1419.5 g/mol
- TB-500 — Formula: C212H350N56O78S · MW: 4963 g/mol
Specifications
- Form: Lyophilized powders (research-grade)
- Purity: ?99% (HPLC); COA per lot available
- Packaging: Sealed vials suitable for laboratory handling
Disclaimer
While HULK MUSCLES strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by HULK MUSCLES.








