GHK-Cu 100 mg — Copper Tripeptide Complex for Regenerative Research
GHK-Cu is a copper(II) complex of the endogenous tripeptide
glycyl-L-histidyl-L-lysine (GHK). It has been studied in preclinical and exploratory
clinical settings for roles in wound repair, skin regeneration, hair biology,
and extracellular-matrix (ECM) remodeling. GHK-Cu is of interest as a
signaling molecule that can influence growth factors, inflammatory mediators,
and matrix-metaloproteinase (MMP) balance in various tissue models.
What It Is
- Class: Endogenous tripeptide–copper complex
- Peptide sequence: Gly-His-Lys (GHK) chelating Cu2+
- Concept: Naturally occurring low–molecular weight peptide
found in plasma and tissues, studied as a regulator of repair and remodeling
processes when complexed with copper.
Proposed Mechanisms (Preclinical)
ECM & Tissue Remodeling
- Explored for stimulation of collagen, elastin, and glycosaminoglycan
synthesis in fibroblast and skin models. - Modulation of MMP/TIMP balance (matrix metalloproteinases and tissue
inhibitors of metalloproteinases) associated with ECM turnover. - Support of wound closure, granulation-tissue quality, and tensile strength
in animal injury models.
Inflammation, Oxidative Stress & Hair Biology
- Investigated for anti-inflammatory and antioxidant-linked
effects, including changes in cytokine and reactive-oxygen–species markers. - Preclinical and cosmetic research on hair-follicle signaling,
anagen/follicle-support markers, and scalp–skin parameters. - Model-dependent changes in angiogenesis and microcirculation in skin and
subcutaneous tissues.
Selected Research Highlights
- Skin Regeneration: GHK-Cu has been studied in creams, solutions, and
injectable formats (research/clinical) for effects on wrinkles, elasticity, and overall
skin appearance, often compared with retinoids or other actives. - Wound-Healing Models: Animal and in vitro work suggests improvements
in wound contracture, epithelialization, and ECM organization vs. controls. - Hair & Scalp: Investigations have examined changes in hair density,
shaft thickness, and scalp quality when GHK-Cu is incorporated into topical formulations. - Systemic Markers: Experimental studies have explored impacts on
oxidative-stress markers, inflammatory mediators, and gene-expression panels related
to repair and aging.
Chemical & Handling Information
- Type: Copper(II) tripeptide complex (GHK-Cu)
- Peptide length: 3 amino acids (glycyl-L-histidyl-L-lysine)
- Appearance: Blue to blue-green lyophilized powder (color may vary by lot
due to copper content and excipients)
Specifications
- Peptide: GHK-Cu
- Amount: 100 mg per vial
- Form: Lyophilized powder
- Purity: ?99% (HPLC); COA per lot available
- Packaging: Sealed vials suitable for standard laboratory handling
Disclaimer
While HULK MUSCLES strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by HULK MUSCLES.








